A member of the National Under 23 team, the Black Meteors, has tested positive after arriving in Japan for a friendly match.
According to the Japan Football Association, the yet-to-be-named player has been isolated from the rest of the squad who are themselves isolated at a designated facility.
The Ghana team arrived on Wednesday for a friendly with the Japanese Olympic Football Team in the southern city of Fukuoka.
Japan is battling a fourth wave of Covid-19 just 50 days before the scheduled start of the Olympic games with Tokyo and other cities under a state of emergency until the 20th of next month.
Ghana will play Japan in two friendly matches scheduled for June 4 and 8 in Tokyo before travelling to South Korea to play them on June 12 and 15 respectively.
Japan and South Korea will use the two games to test their readiness for the Olympic Games football competition.
Goalkeepers: Richmond Ayi (Hearts of Oak), William Esso (Vision FC)
Defenders: Samuel Ashie Quaye (Great Olympics), Frank Assinki (HB Koge), Frank Amoabeng (Cerignola), Ibrahim Moro (Asante Kotoko), Uzair Alhassan (Tamale Utrecht), Abdulai Sabit (Getafe CF)
Midfield: Emmanuel Essiam (Berekum Chelsea), Frimpong Boateng (King Faisal), Patrick Mensah (Heart of Lions), Kwame Adubofuor Poku (Colchester United), Osman Bukari (Genk)
Forwards: Jonah Attuquaye (Legon Cities), Percious Boah (Dreams FC), Samuel Obeng Gyabaa (Real Oviedo), Joselpho Barnes (Shalkeh 04), Diawusie Taylor (Karela United FC), Samuel Boakye (Eleven Wonders)